zndpa-cy7和zndpa-fitc荧光细胞凋亡检测产品综述
西安瑞禧生物科技有限公司新推出2款用于细胞凋亡荧光检测产品zndpa-cy7和zndpa-fitc,如需购买请联系我公司。
产品简介:
利用zndpa与磷脂酰丝氨酸的高度亲和力,通过凋亡细胞外翻的磷脂酰丝氨酸特异性结合(或者细菌表面的磷脂酰丝氨酸)达到检测凋亡细胞或者细菌的目的。
zndpa-cy7产品结构式:
zndpa-fitc产品结构式:
参考文献:
1. hanshaw rg, lakshmi c, lambert tn,johnson jr and and smith bd. fluorescent detection of apoptotic cells by usingzinc coordination complexes with a selective affinity for membrane surfacesenriched with phosphatidylserine. chembiochem 2005, 12, 2214-2220.
2. hanshaw rg and smith bd. new reagentsfor phosphatidylserine recognition and detection of apoptosis. bioorg. &med. chem. 2005, 13, 5035-5042.
3. leevy, w. m.; gammon, s. t.; jiang, h.;johnson, j. r.; maxwell, d. j.; marquez, m.; piwinica-worms, d.; smith, b. d.optical imaging of bacterial infection in living mice using a fluorescentnearinfrared molecular probe. j. am. chem. soc. 2006, 128, 16476-16477.
4. leevy, w. m.; gammon, s. t.; johnson, j.r.; lampkins, a. j.; jiang, h.; marquez, m.; piwinica-worms, d.; smith, b. d.noninvasive optical imaging of staphylococcus aureus bacterial infection inliving mice using a bis-dipicolylamine-zinc (ii) affinity group conjugated to anear-infrared fluorophore. bioconjugate chem. 2008, 19, 686-692.
产品应用:
1、可以代替annexin v-fitc通过激光共聚焦和流式细胞仪实现凋亡细胞的检测;
2、可以实现细胞/活体/组织对细菌的检测;
3、可以实现细胞/活体/组织对凋亡细胞的染色。